Pharmacophore Perception (PRB-1)

The editor developed the book to be applicable to a large and diverse audience. His own Introduction coupled with chapters by the pioneers in pharmacophore perception provide a clear perspective, enabling both novices and experts to appreciate state-of-the-art perception methods described in subsequent chapters.

The editor has also included chapters which discuss applications ranging from qualitative (SAR) methods such as 3D searching and other forms of database mining:  examples include quantitative (QSAR) methods such as CoMFA and receptor-ligand docking scores. Two sections of this book are dedicated to analog-based and receptor-based pharmacophores which comprise today's fundamental approaches to CADD: ligand-based and receptor-based design.

Editor:  Robert S. Pearlman, Ph.D., Chair in Pharmacy and Director, Laboratory for Molecular Graphics and Theoretical Graphics, College of Pharmacy, University of Texas.

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